I read Dune in High School. It's one of my favorites. I never did get around to reading the sequels though. I should definitely get back to that series.
Suffice it to say, I have been pretty impressed with it. My high school reading included a lot of Fritz Lieber and H.P. Lovecraft in particular. A few other things that have struck me about Dune:
* Herbert is very vague as to what the "weirding way of combat" actually is. Lynch interprets this in the context of powerful sonic weapons, but I was surprised to discover that this is no means explicit in the book. And a scene in the film where an aircraft is shot down with a sound projector is paralleled in the book by one where an aircraft is instead shot down with rockets.
* Several of the main characters are very young when the book begins and not much older when it ends (e.g., I think the Paul Atreides and Feyd Rautha are each about 15 when it begins and 18 when it concludes). Sting, however, is 33 when he plays the latter character in Lynch's 1984 film! And Sean Young, whose character Chany is initially described as a "child," is 35. This age disparity, by the way, is something that struck me when I read
Gone with the Wind and compared it with the 1939 film. In the book, men in their 50s routinely court girls in their early teens -- and Rhett Butler is decades older than Scarlet O'Hara -- and this is not reflected in any obvious way in the film.